Persistent pain is the leading cause of years lived with disability worldwide. Research into pain experiences often adopts a humanistic perspective, predominantly relying on interview data and rarely engaging with real-world contexts. The Posthuman Walking Project brought together a transdisciplinary network of individuals with lived experiences of pain alongside academics and clinicians from five countries to collectively explore how posthuman philosophies might challenge human-centered paradigms. Specifically, we used mobile phone video footage to investigate the more-than- human entanglements of walking in the landscape when experiencing pain. This paper reflects on our engagement with the uncertainty and multifaceted nature of exploratory methods and how the process of “becoming posthuman” did not follow a pre-determined path. We outline our rhizomatic methodological approach, emphasizing the contributions of walker-partners, project development meetings, and the value of allowing methods to remain responsive and emergent. Finally, we discuss the complexities of studying the assemblage of humans, walking, pain, and landscape, illuminating the transformative potential of posthuman frameworks in understanding lived experiences of pain.