This article offers a reassessment of late medieval resistance to the Valois monarchy, through examining south-western France in the mid-fifteenth century as a case study. Whereas modern scholarship has often foregrounded Valois success and treated Gascony as sliding inexorably into the maw of the French state, it is shown here that a deep-rooted revolt against King Charles VII occurred in the south-west in 1452-53, in conjunction with Gascon exiles and the English. Influential and durable networks under the leadership of regional nobles were fundamental throughout the movement, and these entities remained a potent force even after it was defeated. Overall, this is indicative of how backing for, and cooperation with, the English in France around the end of the Hundred Years’ War has traditionally been underestimated, and of how noble-led networks retained the ability to underpin and inspire resistance to the French monarchy.