Creatine supplementation research fails to support the theoretical basis for an effect on cognition: Evidence from a systematic review

McMorris, T., Hale, B. J., Pine, B. S. and Williams, T. B. (2024) Creatine supplementation research fails to support the theoretical basis for an effect on cognition: Evidence from a systematic review. Behavioural Brain Research, 466 (114982). pp. 1-11. ISSN 0166-4328

[thumbnail of McMorris, T. et al. Creatine supplementation research fails to support the theoretical basis for an effect on cognition: Evidence from a systematic review, Behavioural Brain Research, Vol 466,2024,114982, https://doi.org/10.1016/j.bbr.2024.114982.] Text (McMorris, T. et al. Creatine supplementation research fails to support the theoretical basis for an effect on cognition: Evidence from a systematic review, Behavioural Brain Research, Vol 466,2024,114982, https://doi.org/10.1016/j.bbr.2024.114982.)
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Text (McMorris, T. et al. Creatine supplementation research fails to support the theoretical basis for an effect on cognition: Evidence from a systematic review, Behavioural Brain Research, Vol 466,2024,114982, https://doi.org/10.1016/j.bbr.2024.114982.)
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Abstract

Creatine supplementation has been put forward as a possible aid to cognition, particularly for vegans, vegetarians, the elderly, sleep deprived and hypoxic individuals. However, previous narrative reviews have only provided limited support for these claims. This is despite the fact that research has shown that creatine supplementation can induce increased brain concentrations of creatine, albeit to a limited extent. We carried out a systematic review to examine the current state of affairs. The review supported claims that creatine supplementation can increases brain creatine content but also demonstrated somewhat equivocal results for effects on cognition. It does, however, provide evidence to suggest that more research is required with stressed populations, as supplementation does appear to significantly affect brain content. Issues with research design, especially supplementation regimens, need to be addressed. Future research must include measurements of creatine brain content.

Publication Type: Articles
Additional Information: © 2024 The Author(s).
Uncontrolled Keywords: energy, ATP. vegetarians, elderly, hypoxia, sleep
Subjects: Q Science > QP Physiology
Divisions: Academic Areas > Institute of Sport
Academic Areas > Institute of Sport > Research Theme > Enhancing Sport Performance
Academic Areas > Institute of Sport > Research Theme > Health and Well-Being
Academic Areas > Institute of Sport > Research Theme > Occupational Performance
Research Entities > Centre for Health and Allied Sport and Exercise Science Research (CHASER)
Academic Areas > Institute of Sport > Research Theme > Nutritional Supplementation
Depositing User: Beverley Hale
Date Deposited: 17 Apr 2024 08:53
Last Modified: 10 Jun 2024 10:24
URI: https://eprints.chi.ac.uk/id/eprint/7473

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