Effect of Intake Duration of Anthocyanin-rich New Zealand Blackcurrant Extract on Cardiovascular Responses and Femoral Artery Diameter during Sustained Submaximal Isometric Contraction

Cook, M. D., Dunne, A., Bosworth, M. and Willems, M. E. T. (2021) Effect of Intake Duration of Anthocyanin-rich New Zealand Blackcurrant Extract on Cardiovascular Responses and Femoral Artery Diameter during Sustained Submaximal Isometric Contraction. Journal of Dietary Supplements, 20 (1). pp. 15-27. ISSN 1939-0211

[thumbnail of This is an Accepted Manuscript of an article published by Taylor & Francis in  Journal of Dietary Supplements on 11 July 2021, available online https://doi.org/10.1080/19390211.2021.1948943] Text (This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Dietary Supplements on 11 July 2021, available online https://doi.org/10.1080/19390211.2021.1948943)
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Abstract

Seven-day intake of anthocyanins from New Zealand blackcurrant (NZBC) extract increased cardiac output and femoral artery diameter during a sustained submaximal isometric contraction. It is not known if there are intake duration effects by NZBC extract on the isometric contraction-induced cardiovascular responses. In a repeated measures design, male participants (n=19, age: 26±4 years) performed a 120-second submaximal (30%) isometric contraction of the knee extensors at baseline and following 1, 4 and 7-days intake of 600 mg·day-1 NZBC extract. During the 120-second submaximal isometric contraction, femoral artery diameter and cardiovascular responses were measured with ultrasound and beat-to-beat hemodynamic monitoring. Femoral artery was larger following 4-days (mean difference=0.046, 95% CI [0.012, 0.080 cm], p=0.005) and 7-days (mean difference=0.078, 95% CI [0.034, 0.123 cm], p<0.001) in comparison to baseline with no increase with 1-day intake. Systolic and diastolic blood pressure, heart rate and total peripheral resistance were not changed by NZBC extract at 1, 4 and 7-days intake. However, mean arterial pressure, stroke volume, cardiac output and total peripheral resistance were changed at time points during the isometric contraction following 7-days intake in comparison to 1-day intake of NZBC extract (p<0.05). Alterations in femoral artery diameter and some cardiovascular responses during a submaximal sustained isometric contraction of the knee extensors are affected by the intake duration of New Zealand blackcurrant extract, with no effects by 1-day intake. Our observations suggest that the bioavailability of blackcurrant anthocyanins and anthocyanin-derived metabolites is required for days to alter the mechanisms for isometric-contraction induced cardiovascular responses.

Item Type: Article
Uncontrolled Keywords: New Zealand blackcurrant; anthocyanins; blood flow; isometric contraction; Food Science; Nutrition and Dietetics; Pharmacology (medical)
Subjects: Q Science > QP Physiology
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Academic Areas > Institute of Sport > Area > Exercise Physiology
Depositing User: Mark Willems
Date Deposited: 01 Jul 2021 11:42
Last Modified: 09 Jan 2023 13:44
URI: https://eprints.chi.ac.uk/id/eprint/5830

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