Whole-body precooling attenuates the extracellular HSP72, IL-6 and IL-10 responses 1 after an acute bout of running in the heat

Lee, B. J., Clarke, N. D., Hankey, J. and Thake, C. D. (2018) Whole-body precooling attenuates the extracellular HSP72, IL-6 and IL-10 responses 1 after an acute bout of running in the heat. Journal of Sports Sciences, 36 (4). pp. 414-421. ISSN 0264-0414

[img]
Preview
Text (This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Sports Sciences on 5 April 2017, available online: http://www.tandfonline.com/10.1080/02640414.2017.1313441.)
Whole body precooling attenuates the extracellular HSP72 IL6 and IL10 responses after an acute bout of running in the heat [11060].pdf - Accepted Version
Available under License Creative Commons Attribution.

Download (873kB) | Preview

Abstract

The impact of whole-body precooling on the extracellular heat shock protein 72 (eHSP72) and cytokine responses to running in the heat is undefined. The aim of this study was to determine whether precooling would attenuate post-exercise eHSP72 and cytokine responses.Eight male recreational runnerscompleted two90-minuteboutsofrunningat65% _VO2maxin32±0.9°Cand47±6%relativehumidity(RH)preceded by either 60-minutes of precooling in 20.3 ± 0.3°C water (COOL) or 60 min rest in an air-conditioned laboratory (20.2 ± 1.7°C, 60 ± 3% RH; CON). eHSP72, TNF-α, IL-6, IL-10 IL-1ra were determined before and immediately after exercise. The elevation in post-exercise eHSP72 was attenuated after COOL (+0.04 ± 0.10 ng.mL−1) compared to CON (+ 0.29 ± 0.26 ng.mL−1;P < 0.001). No changes in TNF-α were observed at any stage. COOL reduced the absolute post-exercise change in IL-6 (P = 0.011) and IL-10 (P = 0.03) compared to CON. IL-1ra followed this trend (P = 0.063). A precooling-induced attenuation of eHSP72 and proinflammatory cytokines may aid recovery during multi-day sporting events, but could be counterproductive if a training response or adaptation to environmental stress is a desired outcome.

Item Type: Article
Subjects: G Geography. Anthropology. Recreation > GV Recreation Leisure > GV557 Sports
Q Science > QP Physiology
Divisions: Departments > Sport and Exercise Sciences
Depositing User: Ben Lee
Date Deposited: 08 Jun 2017 10:39
Last Modified: 16 Oct 2019 15:52
URI: http://eprints.chi.ac.uk/id/eprint/2780

Actions (login required)

View Item View Item