Transcendental materialism is a philosophical perspective that uses German Idealism, Marxism, psychoanalysis and natural science to offer a materialist account of subjectivity and culture. This essay compares this philosophical framework with recent work in the study of religion (Manuel Vásquez) and philosophy of religion (Kevin Schilbrack and Thomas A. Lewis). While transcendental materialism has until now been unconcerned with religion, it offers parallels with this recent work. It differs, however, in its specific understanding of the material dimension of the dialectical relationship between abstraction/conceptuality and practice/embodiment.