The Effects of Creatine Supplementation on Physical Work Capacity at Altitude

Agathanelou, Daniel (2016) The Effects of Creatine Supplementation on Physical Work Capacity at Altitude. Undergraduate thesis, University of Chichester.

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Objective. To investigate the potential ergogenic benefits of creatine supplementation on physical work capacity at altitude, by reducing the inspired oxygen fraction (FiO2). Method. Sixteen healthy, physically fit, male participants (19.7 ± 1.9 years) completed a fixed-work rate exercise test under four conditions: sea level pre-supplementation, altitude pre-supplementation, sea level post-supplementation and altitude postsupplementation. Measurements of arterial oxygen saturation (%, SpO2), peak heart rate (b.min-1), heart rate recovery (b.min-1), blood lactate recovery (mmol/L), mass (kg) and perceived exertion (Borg rating) were recorded during all conditions. Results. A reduction in FiO2 elicited a decline in arterial SpO2 (p<0.0005). With this, there was a significant increase in both peak heart rate and perceived exertion (p <0.0005). As expected, both heart rate recovery and blood lactate recovery were delayed as a result (p<0.0005). Post-supplementation, no significant changes to physical work capacity could be reported, although there was a noticeable reduction in perceived exertion and body mass trended toward a significant increase in the creatine group (p =0.077). A significant interaction was found for creatine affecting physical work capacity at altitude, however this was later deemed an anomaly in the data. Conclusion. Physical work capacity during exercise of a fixed-rate at altitude was not affected following 6 days of creatine supplementation. However, significant impairments to many physiological mechanisms were observed during the conditions involving reduced FiO2. A large amount of individual variation was displayed, suggesting different individual tolerances to performing in a hypoxic environment.

Item Type: Thesis (Undergraduate)
Additional Information: BA (Hons) Adventure Education
Uncontrolled Keywords: Physical Work Capacity, Creatine Supplementation, Altitude, Acute Exposure, Hypoxia, Hypoxaemia, Arterial Oxygen Saturation, Heart Rate, Blood Lactate, Perceived Exertion, Recovery
Subjects: Q Science > QP Physiology
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Departments > Adventure Education
Undergraduate Dissertations
Depositing User: Ann Jones
Date Deposited: 10 Jan 2017 11:30
Last Modified: 10 Jan 2017 12:11

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