Effect of acute normobaric hypoxia on the ventilatory threshold

Gallagher, Carla A., Willems, Mark E. T., Lewis, Mark P. and Myers, Stephen D. (2014) Effect of acute normobaric hypoxia on the ventilatory threshold. European Journal of Applied Physiology, 114 (8). pp. 1555-1562. ISSN 1439-6319

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Abstract

PURPOSE:
This study investigated the response of the ventilatory threshold (VT) to acute normobaric hypoxia and compared the agreement between software-based algorithms which use automatic detection to identify the VT. Results were used to examine whether the VT can be used as a physiological parameter to prescribe and monitor exercise intensity in hypoxic exercise training programs.
METHODS:
Fourteen untrained individuals (7 women, 7 men; age 22 ± 2 years, [Formula: see text]O2peak 46 ± 7 mL kg(-1) min(-1)) completed five identical graded exercise tests (randomized order) on a cycle ergometer to measure VT at sea-level (SL) and in response to four normobaric hypoxic conditions (FIO2: 0.185, 0.165, 0.142, 0.125) equivalent to 1,000, 2,000, 3,000 and 4,000 m. Data were analyzed using a one-way analysis of variance (ANOVA) with repeated measures.
RESULTS:
The VT was similar across all conditions (SL = 1.98 ± 0.46, 1,000 m = 2.03 ± 0.61, 2,000 m = 2.27 ± 0.62, 3,000 m = 1.84 ± 0.50, 4,000 m = 2.29 ± 0.58 L min(-1)) for all algorithms used despite a reduction in arterial oxygen saturation at 3,000 (P ≤ 0.01) and 4,000 m (P ≤ 0.01) compared with SL values.
CONCLUSION:
The VT appears to be a suitable physiological parameter for exercise prescription in normobaric hypoxia up to an altitude of 4,000 m.

Item Type: Article
Uncontrolled Keywords: Normobaric hypoxia, exercise prescription, cycle ergometry, ventilatory threshold, altitude
Subjects: Q Science > QP Physiology
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Departments > Sport and Exercise Sciences
Depositing User: Mark Willems
Date Deposited: 04 Jun 2014 10:31
Last Modified: 26 Mar 2019 12:19
URI: http://eprints.chi.ac.uk/id/eprint/1201

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